Tired of your horse tying up? Named after JC Howe who invented the formula over sixty years ago, this all-natural supplement helps stop muscle cramping without side effects. Trainers say one tube can end tie-up for 30 days. Treat in the morning before vigorous activity. Each dose contains (min) 65 mg thiamine, 670 mg niacinamide, 43 mg vitamin B₆, 34 mg d-pantothenic acid, 26 mg riboflavin and 0.04 mg vitamin B₁₂. Dosage: Administer 10 cc to back of horse's throat on 1st, 2nd and 4th days; skip 3rd day.